Tempanil Extra 500mg+65mg

Tablet
Paracetamol + Caffeine
Amulet Pharmaceuticals

Other Strength:
- Tempanil 500mg

Alternative:
- Fast PLUS 500mg+65mg
- Reset Plus 500mg+65mg
- Ace Plus 500mg+65mg
- Cafedon 500mg+65mg
- Feva Plus Tablet 500mg+65mg
- Xcel Plus 500mg+65mg
- Pamix Extra 500mg+65mg
- Pyrexil Plus 500mg+65mg
- P+C 500mg+65mg
- Reliv Plus 500mg+65mg
- Benalgin Plus 500mg+65mg



Tempanil Extra
COMPOSITION:
TEMPANIL EXTRA Tablet: Each film coated tablet contains Paracetamol BP 500 mg and Caffeine BP 65 mg.

PHARMACOLOGY:
TEMPANIL EXTRA Tablet is the combination of Paracetamol and Caffeine. It has analgesic and antipyretic properties. The presence of Caffeine increases the analgesic effect of Paracetamol. Paracetamol is one of the safest and most widely used analgesic and antipyretic. It produces analgesic action by elevation of the pain threshold and antipyresis through action on the hypothalamic heat regulating center. Caffeine is an alkaloid which is a theophylline – like Xanthine derivative. By intermolecular association with Paracetamol, Caffeine increases the solubility and transmembrane permeation of Paracetamol. In addition caffeine increases the pain threshold and tolerance of pain.

Caffeine has also an intrinsic power to raise vessel tone in the cranial of the brain, which provides another benefit to treat migraine and headache.

INDICATION:
The indications are as follows

– Headache Migraine

-Toothache Neuralgia

– Feverishness Period pain

-Sore throat Backache

-Helps reduce temperature Aches and pain of colds and flu

DOSAGE & ADMINISTRATION:
Adults: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily. Not recommended for children below 12 years.

SIDE-EFFECT:
Side effects of paracetamol are usually mild, though haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.

CONTRAINDICATIONS:
The fixed-dose combination is contra-indicated in individuals who have shown a previous Hypersensitivity to these ingredients.

PRECAUTIONS:
Should be given cautiously in the following cases: In patients with hepatic or renal failure.
In patients taking other hepatotoxic medication. Prolonged use of the drug without consulting a physician should be avoided.

USE IN PREGNANCY AND LACTATION:
Although there is epidemiological evidence of the safety of Paracetamol in pregnancy& lactation, medical advice should be sought before using this product.

DRUG INTERACTION:
It increases the effect of chloramphenicol and coumarin anticoagulant. Risk of hepatotoxicity of paracetamol may be increased in alcoholics or in patients taking other anti-epilectic medications.

OVERDOSAGE:
Symptoms of Paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 40 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur.

STORAGE:
Store in a cool, dry place, away from light. Keep out of reach of children.

HOW SUPPLIED:
TEMPANIL EXTRA Tablet: Box containing 20×10’s tablets in blister pack.

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