Dirin 10mg

Tablet
Dicycloverine Hydrochloride
Alco Pharma

Other Strength:

Alternative:
- Loverin 10mg
- Cyclopan 10mg
- Colicon® 10mg
- Diverin 10mg
- Abdorin 10mg



Dirin
Description:
Dicycloverine Hydrochloride is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulate muscles by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscles. Dicycloverine is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Dicycloverine inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.

Composition:
Each tablet contains Dicycloverine Hydrochloride BP 10 mg.
Each 5 ml Syrup contains Dicycloverine Hydrochloride BP 10 mg.

Indication/Use:
Irritable bowel syndrome (Diarrhea Predominant)
Infantile colic
GIT spasm
Diverticulitis
Abdominal colic
Diarrhea
Dysentery

Dosage Guideline:
Adults : 10 to 20 mg three to four times a day. Maximum recommended
oral dose is 160 mg daily in divided dose.
Children : Children over 6 months of age- 5 to 10 mg three times a day.

Side Effects:
Insomnia, headache, weakness, confusion, increased ocular tension, urinary hesitancy,
palpitations etc.

Contraindication:
Dicycloverine Hydrochloride is contraindicated in obstructive uropathy, obstruction disorder in GIT, severe ulcerative colitis, unstable cardiovascular status in acute hemorrhage, glucoma, myasthenia gravis and patients with hypersensitivity to Dicycloverine Hydrochloride and infants less than 6 months of age.

Drug Interaction:
The following agents may increase certain actions or side-effects of Dicycloverine e.g. antiarrhythmic agents, antihistamines, antipsychotic agents, benzodiazepines, MAO inhibitors, narcotic analgesics, nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants and other drugs having anticholinergic activity.

Use in Pregnancy & Lactation:
Pregnancy Category B. Dicycloverine was neither teratogenic nor embryocidal in animal
trial. Like other drugs it should be used during pregnancy only if clearly needed. There
are evidences on the secretion of this drug into breast milk. Dicycloverine should not be
used in case of lactating mother.

Over Dose:
Toxic reaction seldom occurs with dicycloverine. The signs and symptoms of overdose
are headache; nausea; vomiting; blurred vision; dilated pupils; hot & dry skin; dizziness;
dryness of the mouth; difficulty in swallowing; and CNS stimulation.

Precaution:
Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, known or suspected prostatic hypertrophy.

Therapeutic Class:
Anticholinergics

Dosage Form:
Tablet
Syrup

Storage:
Store in a cool, dry place & protect from light. Keep out of the children reach.

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