Diaprid 80mg

Tablet
Gliclazide
Alco Pharma

Other Strength:

Alternative:
- Diapro 80mg
- GLICLID 80mg
- Consucon 80mg
- Gluzit 80mg
- Lozide 80mg
- Glucoact 80mg
- Admira 80mg
- Glucozid 80mg
- Claz 80mg
- Diglic 80mg
- Sugred 80mg
- Glicron 80mg



Diaprid
Description:
Diaprid (Gliclazide) is a second generation sulfonylurea drug that has hypoglycemic and potentially useful haemobiological properties. It stimulates the release of insulin from pancreatic beta-cells by facilitating Ca2+ transport across the beta-cell membranes and decreases hepatic glucose output.

Composition:
Diaprid Tab: Each tablet contains Gliclazide BP 80 mg.

Indication/Use:
In type-II diabetes mellitus, when diet and exercise is not sufficient to obtain normal blood glucose level.

Dosage Guideline:
The usual initial dose is 40-80 mg daily, gradually increased, if necessary, up to 320 mg daily until adequate control is achieved. A single dose should not exceed 160 mg. When higher doses are required it should be taken twice daily.

Side Effects:
There may be hypoglycemia in concurrent conditions such as hepatic and renal disease, malnutrition, alcohol intoxication. Sometimes headache, gastrointestinal upsets, nausea, dizziness, skin reactions including rash, pruritus and erythema may occur.

Contraindication:
Gliclazide should not be used in -
* Juvenile-onset (type - I) diabetes
* Diabetes associated with Ketosis
* Diabetic patients undergoing surgery, after severe injury or during infection
* Patients having hypersensitivity for sulfonylurea group of drugs
* Pregnant women and breast-feeding mother
* Hepatic insufficiency

Drug Interaction:
The hypoglycemic effects of Gliclazide may be increased by Aspirin, NSAIDs, Phenylbutazone, Clofibrate, Sulfonamide, Cimetidine, Imidazole antifungal agents and Monoamine Oxidase inhibitors. The hypoglycemic effect of Gliclazide sometimes may be reduced by Rifampin, Barbiturates, Phenytoin, Thiazide diuretics, Diazoxide, Glucocorticoids, Estrogens, Sympathomimetic drugs.

Use in Pregnancy & Lactation:
Gliclazide should not be used in pregnancy and nursing mother.

Precaution:
Gliclazide should be used carefully in patients with hepatic impairment. If there is definite hepatic disease then Gliclazide should not be used. Gliclazide can be used safely in patients with renal insufficiency as it is extensively metabolized. Consucon has less sudden hypoglycemic episode than other sulfonylurea group of drugs.

Therapeutic Class:
Antidiabetic

Dosage Form:
Tablet

Storage:
Store in a cool, dry place & away from light. Keep medicines out of reach of children.

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