Claz 80mg

Tablet
Gliclazide
Astra Bioparmaceuticals

Other Strength:

Alternative:
- Diapro 80mg
- GLICLID 80mg
- Consucon 80mg
- Gluzit 80mg
- Lozide 80mg
- Glucoact 80mg
- Admira 80mg
- Diaprid 80mg
- Glucozid 80mg
- Diglic 80mg
- Sugred 80mg
- Glicron 80mg



Claz
Composition
Claz: Each tablet contains Gliclazide BP 80 mg.

Description
Claz (Gliclazide) is a second generation sulfonylurea drug that has hypoglycaemic and potentially useful haemobiological properties. It stimulates the release of insulin from pancreatic beta-cells by facilitating Ca+2 transport across the beta-cell membranes and decreases hepatic glucose output.

Indications
Claz is indicated for the treatment of type 2 diabetes mellitus.

Dosage & Administration
Claz: The usual initial dose is 40 to 80 mg daily. The dose can be increased upto 320 mg daily in divided doses when needed. The drug should be taken before meal.

Side Effects
There may be hypoglycaemia in concurrent conditions such as hepatic and renal disease, malnutrition, alcohol intoxication. Sometimes headache, gastrointestinal upsets, nausea, dizziness, skin reactions including rash, pruritus, erythema may occur.

Precautions
Gliclazide should be used carefully in patients with hepatic impairment. If there is definite hepatic disease then gliclazide should not be used. Claz (Gliclazide) can be used safely in patients with renal insufficiency as it is extensively metabolized. Claz has less sudden hypoglycaemic episode than other sulfonylurea group of drugs.

Contraindications
Gliclazide should not be used in –
Juvenile-onset (type – I) diabetes
Diabetes associated with Ketosis
Diabetic patients undergoing surgery, after severe injury or during infection
Patients having hypersensitivity for sulfonylurea group of drugs
Pregnant women and breast-feeding mother
Hepatic insufficiency

Use in Pregnancy & Lactation
Pregnant Women: Gliclazide should not be used in pregnant women although animal studies of Gliclazide have not shown any teratogenic effect.
Nursing Mothers: This drug is contraindicated when breast feeding.

Overdose
In accidental overdose, at first gastric lavage should be done and at the same time the hypoglycaemia should be corrected. In severe cases I/V infusion of 5% glucose should be started immediately with frequent monitoring of blood glucose and potassium level.

Storage
Store in a cool and dry place, below 30°C and away from light.

How Supplied
Claz: Each box containing 3 x 10’s tablets in blister pack.

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