Napro 500mg

Tablet
Naproxen Sodium
Aristo pharma

Other Strength:
- Napro-A 250mg
- Napro-A Plus 500mg+20mg
- Anaprox 500mg
- Napro 250mg
- Naproben 500mg
- Naproben Plus 500mg+20mg
- Napro-A Plus 375mg+20mg
- Napro-A 500mg
- Xenapro Plus 500mg+20mg
- Xenapro 500mg

Alternative:
- Nuprafen 500mg
- Sonap 500mg
- Napryn 500mg
- Anaflex 500mg
- Anaflex SR 500mg
- Napren 500mg
- Xenap 500mg
- Naproben 500mg
- Ultranax 500mg
- Napro-A 500mg
- Xenapro 500mg



Napro
Presentation:
Napro Tablet: Each tablet contains Naproxen BP 250 mg.
Napro-500 Tablet: Each tablet contains Naproxen BP 500 mg.

Indications:
Napro is indicated in inflammatory rheumatic diseases, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, in soft tissue rheumatism & musculoskeletal disorders, acute gout, dysmenorrhoea etc.

Dosage & Administration:
1. Rheumatic disorders: the usual initial dose of naproxen is 250 mg twice daily adjusted to 500 mg to 1000 mg daily in 2 divided doses.

2. Juvenile arthritis: A dose of 10 mg/kg body weight daily in 2 divided doses is used for children over 5 years of age.

3. Acute gout: An initial dose of 750 mg followed by 250 mg every 8 hours.

4. Dysmenorrhoea: 500 mg may be given initially followed by 250 mg in every 6-8 hours.

Contrainidications:
History of asthma attacks or urticaria triggered by acetylsalicylic acid or other prostaglandin synthesis inhibitors.

Warning & Precautions:
Use of Naproxen should be avoided in patients with gastrointestinal disorders and gastro-duodenal ulcer. In case of severe hepatic or renal damage or disturbance of cardiac function a close medical surveilance is indicated. Blood counts including platelet counts, as well as monitoring of hepatic and renal functions are recommended, particularly in patients under long-term therapy.

Side effects:
Naproxen is generally well tolerated, but occasionally patient may complain gastric discomfort, nausea & dizziness. In exceptional cases, very sensitive patients may suffer from gastro-intestinal bleeding, skin rashes, thrombocytopenia.

Drug interaction:
Antacid: The absorption of naproxen can be altered by antacids.
Aspirin: Plasma concentration of Naproxen can be reduced when aspirin is given concomitantly, this appeared to be due to increased exeretion of naproxen.
Diuretics: Naproxen diminish the effect of frusemide.
Probenecid: It increase the plasma concentration of Naproxen.

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