Flocip 500mg

Tablet
Ciprofloxacin
Amulet Pharmaceuticals

Other Strength:

Alternative:
- Rocipro 500mg
- Civox 500mg
- Floxabid 500mg
- Quintor 500mg
- Quinocin 500mg
- Ancipro 500mg
- Cipex 500mg
- Dumaflox 500mg
- Aprocin 500mg
- Ciflocin 500mg
- Benprox 500mg
- Ciprocin 500mg
- Cipro-A 500mg
- Neofloxin 500mg
- Flontin 500mg



Flocip
DESCRIPTION:
Flocip (Ciprofloxacin) is a synthetic quinolone antibacterial agent having broad-spectrum activity. In vitro studies have shown that the antibacterial action of ciprofloxacin results from the inhibition of bacterial DNA gyrase. This mode of action differs from that of penicillins, cephalosporins, aminoglycosides and tetracyclines and therefore, organisms resistant to these antibiotics are generally sensitive to ciprofloxacin. It is active against most gram-negative aerobic bacteria including Enterobacteriaceae and Pseudomonas aeruginosa. Ciprofloxacin is also active against gram-positive aerobic bacteria including penicillinase producing, non-penicillinase-producing and methicillin resistant staphylococci, although many strains of streptococci are relatively resistant to the drug.
Following oral administration it is rapidly and well absorbed from the GI tract. It is widely distributed into body tissues and fluids. The half-life is about 3.5 to 4.5 hours. About 30 to 50% of an oral dose of Ciprofloxacin is excreted in the urine within 24 hours as unchanged drug and biologically active metabolite.

COMPOSITION:
Flocip 500: Each film coated tablet contains Ciprofloxacin hydrochloride USP equivalent to Ciprofloxacin USP 500 mg.
Flocip Powder for suspension: When reconstituted each 5ml suspension contains Ciprofloxacin hydrochloride USP equivalent to Ciprofloxacin USP 250 mg.

INDICATION:
Flocip is medicated for the treatment of following infections:
In the majority of other infections, 500 mg twice daily should be administered.
Adolescents and children:
Dosage should be 7.5-15 mg/Kg/day depending upon the severity of infection, administered in two divided doses.

CONTRAINDICATION:
Ciprofloxacin is contraindicated in patients who have shown hypersensitivity to ciprofloxacin or other quinolones.

PRECAUTION:
Ciprofloxacin should be used with caution in patients with a history of convulsive disorders. Crystalluria related to the use of Ciprofloxacin has been observed very rarely. Patients receiving Ciprofloxacin should be well hydrated and excessive alkalinity of the urine should be avoided.

SIDE EFFECT:
Side effects include nausea and other gastrointestinal disturbances, headache, dizziness and skin rashes. Crystalluria has occurred with high doses.

DRUG INTERACTION:
Increased plasma levels of theophylline have been observed following concurrent administration with ciprofloxacin. Phenytoin level may be altered when ciprofloxacin is used concomitantly. Ciprofloxacin should not be administered within 4 hours of medications containing magnesium, aluminium, calcium or iron salts, as interference with absorption may occur.

USE IN PREGNANCY AND LACTATION:
Not to be used in pregnancy and nursing stage. Though not recommended for the children where benefit out /weighs risk a dosage of 7.5 – 15 mg/kg/day in two divided doses can be given.

STORAGE:
Store in a cool and dry place, away from light. Keep out of the reach of the children.

HOW SUPPLIED:
Flocip 500 Tablet: Each carton contains 3 X 10’s tablets in blister pack.
Flocip Powder for Suspension:
Dry powder for reconstituting 60 ml suspension in an amber glass bottle for powder and another bottle for diluent with measuring cup.

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