Nixpan 40mg

Tablet
Pantoprazole
Ad-din Pharmaceuticals

Other Strength:
- Nixpan 20mg

Alternative:
- Pantobex 40mg
- PROTOCID 40mg
- Pregel 40mg
- Pantogut 40mg
- Pantex 40mg
- Pantodac 40mg
- Prilosec 40mg
- Pantopra 40mg
- Proton-P 40mg
- Pantotop 40mg
- Trupan 40mg
- Protonil 40mg



Nixpan
COMPOSITION

Nixpan 20 Tablet: Each tablet contains Pantoprazole INN 20 mg (as Pantoprazole Sodium Sesquihydrate). Nixpan 40 Tablet: Each tablet contains Pantoprazole INN 40 mg (as Pantoprazole Sodium Sesquihydrate).

INDICATIONS

Benign gastric ulcer, duodenal ulcer, Gastroesophageal reflux disease (GERD), NSAID induced peptic ulcer, acid hypersecretory conditions including Zollinger-Ellison syndrome, eradication of Helicobacter pylori (in combination with Antibiotics), ulcer resistant to H2- receptor antagonists.

DOSAGE & ADMINISTRATION

Benign gastric ulcer: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks if not fully healed. Duodenal ulcer: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed. GERD: 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks if not fully healed. NSAIDs induced peptic ulcer: 20 mg daily. Acid hypersecretory conditions including Zollinger-Ellison syndrome: Initially 80 mg once daily adjusted according to response (Elderly – max. 40 mg daily), daily doses above 80 mg given in two divided doses. Eradication of Helicobacter pylori: 40 mg twice daily by triple therapy with antibiotics. Ulcer resistant to H2 receptor antagonists: 40 mg once daily for 8 weeks. Maintenance therapy: 20 mg daily, increased to 40 mg daily if symptoms return. Safety and effectiveness in case of children have not been established.

CONTRAINDICATIONS

It is contraindicated in patients with known hypersensitivity to the active drug or any other components of the formulation.

PRECAUTIONS

Patients should be cautioned that this tablet should not be split, crushed or chewed. The tablet should be swallowed whole, with or without food in the stomach.

SIDE EFFECTS

Nixpan (Pantoprazole) is well tolerated in both short term and long term treatment. Headache and diarrhea are the most common side effects and rarely included abdominal pain, flatulence, rash, eructation, insomnia, hyperglycemia.

DRUG INTERACTIONS

Nixpan (Pantoprazole) may interfere with absorption of drugs where gastric pH is an important determinant of their bioavailability (eg, ketoconazole, ampicillin esters, and iron salts).

USE IN PREGNANCY AND LACTATION

There are no adequate and well-controlled studies in pregnant women, the drug should be used during pregnancy only if clearly needed. Nixpan (Pantoprazole) excretion in human milk has been detected in a study of a single nursing mother after a single 40 mg oral dose. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother.

STORAGE PRECAUTIONS

Store in a cool and dry place, protect from light and moisture. Keep out of the reach of the children.

COMMERCIAL PACK

Nixpan 20 Tablet: Box containing 5 x 10 tablets in blister pack. Nixpan 40 Tablet: Box containing 5 x 10 tablets in blister pack.

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