Loreta 2.5mg

Tablet
Letrozole
Popular Pharmaceuticals Ltd

Other Strength:

Alternative:
- Femzole 2.5mg
- Fezol 2.5mg
- Endofree 2.5mg
- Lerozol® 2.5mg
- Arofrez 2.5mg
- Ovazol 2.5mg
- Letrol 2.5mg



Loreta
Indication

Loreta is an aromatase inhibitor indicated for:
-- Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer.
-- Extended adjuvant treatment of postmenopausal women with early breast cancer who have received prior standard adjuvant tamoxifen therapy.

-- First and second-line treatment of postmenopausal women with hormone receptor positive or unknown advanced breast cancer.


Dosage & Administration

Loreta tablets are taken orally without regard to meals.
Recommended dose: 2.5 mg once daily.


Precautions

Use of Letrozole may cause decreases in bone mineral density (BMD). Consideration should be given to monitoring BMD. Updated results from the BMD sub-study demonstrated that at 2 years patients receiving Loreta had a median decrease from baseline of 3.8% in hip BMD compared to a median decrease of 2.0% in the placebo group. The changes from baseline in lumbar spine BMD in Loreta and placebo treated groups were not statistically different.

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