Clavurox 500mg+125mg

Tablet
Cefuroxime Axetil + Clavulanic Acid
Popular Pharmaceuticals Ltd

Other Strength:
- Clavurox 250mg+62.50mg

Alternative:
- Furotil Plus 500mg+125mg
- Cerox CV 500mg+125mg
- Xiclav 500mg+125mg
- Claviator-CV 500mg+125mg
- Axeclav 500mg+125mg
- Axim CV 500mg+125mg
- Benkill CV 500mg+125mg
- Cefotil Plus 500mg+125mg
- Famiclav 500mg+125mg
- Turboclav 500mg+125mg
- Furoclav 500mg+125mg



Clavurox
Indication

Pharyngitis/Tonsillitis caused by Streptococcus pyogenes.

Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase producing strains), Moraxella Catarrhalis (including beta-lactamase producing strains) or Streptococcus pyogenes.

Acute Bacterial Maxillary Sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains only).

Lower Respiratory Tract Infections including pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase and non penicillinase producing strains), Streptococcus pyogenes, Escherichia coli.

Acute Bacterial Exacerbations of Chronic Bronchitis and Secondary Bacterial Infections of Acute Bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains).

Skin and Skin-Structure Infections caused by Staphylococcus aureus (penicillinase and non-penicillinase producing strains), Streptococcus pyogenes, Escherichia coli, Klebsiella spp. and Enterobacter spp.

Urinary Tract Infections caused by Escherichia coli or Klebsiella pneumoniae.

Bone and Joint Infections caused by Staphylococcus aureus (penicillinase and non-penicillinase producing strains).

Uncomplicated and Disseminated Gonococcal Infections due to Neisseria gonorrhoeae (penicillinase and non-penicillinase producing strains) in both males and females.

Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi.

Septicemia caused by Staphylococcus aureus (penicillinase and non-penicillinase producing strains), Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae (including ampicillin-resistant strains) and Klebsiella spp.

Meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (including ampicillin resistant strains) Neisseria meningitis and Staphylococcus aureus (penicillinase and non-penicillinase producing strains).

Switch Therapy (injectable to oral) after surgery when patient's condition is improved.


Dosage & Administration

Adolescents & Adults:





Infection


Dosage


Duration (days)

Pharyngitis or Tonsillitis


250 mg b.i.d


10

Acute Bacterial Maxillary Sinusitis


250 mg b.i.d


10

Acute Bacterial Exacerbation of Chronic Bronchitis
250-500 mg b.i.d

10

Secondary Bacterial Infections of Acute Bronchitis


250-500 mg b.i.d


5-10

Community Acquired Pneumonia


250-500 mg b.i.d


5-10

Complicated Skin & Skin-Structure Infections


250-500 mg b.i.d


10

MDR Typhoid Fever


500 mg b.i.d


10-14

Uncomplicated Urinary Tract Infection


250 mg b.i.d


7-10

Uncomplicated Gonorrhea


1000 mg b.i.d


single dose

Lyme Disease


500 mg b.i.d


20



Paediatric patients (3 months to 12 years) :

Infection


Dosage


Duration (days)

Pharyngitis or Tonsillitis


20 mg/kg/day in two divided doses


5-10

Acute otitis media


30 mg/kg/day in two divided doses


10

Acute bacterial maxillary sinusitis


30 mg/kg/day in two divided doses


10

Community acquired pneumonia


30 mg/kg/day in two divided doses


5-10

MDR Typhoid fever


30 mg/kg/day in two divided doses


10-14

Complicated skin & skin-structure infections


30 mg/kg/day in two divided doses


10

Uncomplicated urinary tract infection


20 mg/kg/day in two divided doses


7-10





Directions for reconstitution of suspension
Shake the bottle well to loosen the powder. Now pour the diluents completely into the bottle of powder. Close the bottle tightly & shake vigorously until it is properly mixed. The suspension is ready for use. After reconstitution the suspension may be used within 10 days if kept at normal temperature or within 14 days if kept in refrigerator.


Precautions

Cefuroxime & Clavulanic Acid should be given with care to patients receiving concurrent treatment with potent diuretics & who have history of colitis.



Use in Pregnancy & Lactation
During pregnancy: While all antibiotics should be avoided in the first trimester if possible. However, Cefuroxime & Clavulanic Acid can be safely used in later pregnancy to treat urinary and other infections.
During lactation: Cefuroxime & Clavulanic Acid is excreted into the breast milk in small quantities. However, the possibility of sensitizing the infant should be kept in mind.

এই পাতাটি ৩০২ বার দেখা হয়েছে