Zepam 3mg

Tablet
Bromazepam
ACI Pharmaceuticals

Other Strength:
- Azepam 5mg

Alternative:
- Nightus 3mg
- TENIL 3mg
- Siesta 3mg
- Laxyl® 3mg
- Lexopil 3mg
- Zerotens 3mg
- Anxio 3mg
- Brozep 3mg
- Notens 3mg
- Benzopam 3mg
- Norry 3mg



Zepam
Description
Bromazepam is an anti-anxiety treatment and a sedative. Bromazepam is in the group of drugs known as benzodiazepines, a class of antidepressants, anti-panic agents, and muscle relaxants. Bromazepam is usually used as a short term treatment for major anxiety, but is not recommended for use to relieve everyday stress or anxiety. This medication may also be used to relieve temporary insomnia, but if used daily, it will become ineffectivein a few weeks.

Indication
1. Emotional disturbances: Acute tension and anxiety states, Difficulties in interpersonal contact, Agitation, Insomnia, anxious and agitated depressive reactions.
2. Functional disturbances in the cardiovascular and respiratory systems: Pseudoangina pectoris, Precordial anxiety, tachycardia, emotiogenic hypertension, dyspnea and hyperventilation.
3. In the gastrointestinal systems: Irritable bowel syndrome, epigastric pain, spasm, bloating, diarrhoea
4. In the genitourinary system: Irritable bladder and dysmenorrhoea.
5. Psychosomatic disorder: Psychogenic headache, psychogenic dermatosis, asthma, gastric and duodenal ulcer, ulcerative colitis.
6. Emotional reactions due to chronic organic diseases
7. Adjuvant to psychotherapy in psychoneurosis

Dosage and administration
Average dosing for outpatient therapy: 1.5-3mg up to three times daily. Severe cases, especially in hospitals: 6-12mg two or three times daily. Treatment of outpatients should begin with low doses, gradually increasing to as short as possible. The overall treatment generally should not be more than 8-12 weeks, including a tapering-off process.

Special dosage instructions:
Zepam®is usually not indicated in children, but if the physician feels Zepam®treatment is appropriate, then dose should be adjusted to their low body weight (about 0.1-0.3mg/kg). Elderly patient and those with impaired hepatic function require lower doses because of individual variations in sensitivity and pharmacokinetic.

Side-effects
The following undesirable effects may occur: Fatigue, drowsiness, muscle weakness, blunting of feelings, reduced alertness, confusion, headache, dizziness, ataxia and diplopia. These symptoms disappear with the continuation of treatment. Drug interaction: As with all psychoactive substances, the effect of Zepam®may be intensified by alcohol. Simultaneous intake of alcohol should be avoided. When Zepam®is combined with other centrally acting drugs such as antidepressants, hypnotic, narcotic analgesics, narcoleptics, anxiolytics/sedatives, antiepileptics, sedative antihistamines, or ansthetics, its CNS sedative effect may be increased.

General precautions
The patientshould be checked regularly at the start of the treatment in order to minimize the dosage and/ or the frequency of administrations and to prevent overdose due to accumulation. Pregnancy and nursing mother: the safety of Bromazepam in pregnant women has not been established. Bromazepam should not be taken during pregnancy unless there is a compellingindications for its use and no safer therapeutic alternative is available. As benzodiazepines are excreted in breast milk, nursing mother should not take Zepam®.

Contra-indications
Zepam®must not be administered to patients with known hypersensitivity to benzodiazepines, severe respiratory insufficiency or sleep apnea syndrome. Precautions: Dependence: The use of benzodiazepines and Benzodiazepine-like agents may lead to development of physical and psychological dependence upon these products. Withdrawal: once physical dependence has developed termination of treatment will be accompanied by withdrawal symptoms. These may consist of headache, muscle pain, extreme anxiety, tension, restlessness, confusion and irritability. Amnesia: Anterograde amnesia may occur using higher therapeutic dosages (documented as 6 mg) the risk increasing at higher dosages. Duration of treatment: at the start of treatment it may be useful to inform the patient that the duration of treatment will be limited and that of dose will be tapered off at the end of treatment.

Overdosage
As with other benzodiazepines, intentional or accidental overdosage of Zepam®is seldom life threatening unless other CNS depressants (including alcohol) have been taken
simultaneously. Overdosage of benzodizepines generally manifests itself in the form of CNS depression ranging from drowsiness to coma. Following overdose with oral benzodiazepines, vomiting should be induced (within 1 hour) if the patient is conscious or gastric lavage undertaken if the patient is unconscious. When no benefit is to be expected from evacuation of stomach, activated charcoal should be administered to reduce intestinal absorption.

Pharmaceutical precautions
Store in a cool and dry place, protect from light.

Presentation
Zepam®3mg tablet: round, light colored tablet with a breakline on one side embossed with 'ACI' in a circle. Each tablet contains Bromazepam BP 3mg.

Package quantities
Zepam®3mg Tablet: Cartons of 100tablets in Alu-Pvc blister.

এই পাতাটি ২৮৫ বার দেখা হয়েছে