Anxio 3mg

Tablet
Bromazepam
Unimed Unihealth MFG. Ltd

Other Strength:

Alternative:
- Nightus 3mg
- TENIL 3mg
- Siesta 3mg
- Laxyl® 3mg
- Lexopil 3mg
- Zerotens 3mg
- Zepam 3mg
- Brozep 3mg
- Notens 3mg
- Benzopam 3mg
- Norry 3mg



Anxio
Presentation
Anxio tablet: Yellow, diamond shaped, scored tablet, each tablet contains bromazepam BP 3mg.

Indications
Anxio (bromazepam) indicated for symptomatic relief of tension, anxiety and agitation.

Dosage and administration
Average dose for ambulatory patients: Bromazepam 3 mg (Anxio one tablet) two or three times daily. It is often an advantage to make the evening dose larger than other doses, or when the total dose is low (e.g: 3 or 6 mg), to give the total dose in the evening. Severe hospitalized cases: 6 to 12 mg two or three times daily.

Contra-indications, warnings, etc.
Patients with known hypersensitivity to benzodiazepines. Patients with chronic obstructive airways disease with incipient respiratory failure. Bromazepam is also contra-indicated in patients with severe hepatic insufficiency, sleep apnoea syndrome, myasthenia gravis.

Precautions: Patients with known or presumed dependence on alcohol or drugs should not take benzodiazepines unless under medical supervision. As with other benzodiazepines, when treatment is suddenly withdrawn, a temporary increase in sleep disturbance can occur after use of bromazepam.

Use in pregnancy and lactation: Pregnancy category C. Benzodiazepines cross the placenta and may cause hypotonia, reduced respiratory function and hypothermia in the newborn infant. As benzodiazepines pass into breast milk, breastfeeding mothers should not take bromazepam.

Use in children: Bromazepam is not recommended for use in children due to insufficient evidence of safety and efficacy in this age group.

Drug interactions: The benzodiazepines, including bromazepam, produce additive CNS depressant effects when co-administered with other medications which themselves produces CNS depression e.g: barbiturates, alcohol, sedatives, antidepressants, hypnotics, anxiolytics, phenothiazines and other antipsychotics, skeletal muscle relaxants, antihistamines, narcotic analgesics and anaesthetics. Bromazepam undergoes hepatic microsomal oxidation via the cytochrome P450 liver enzymes. Therefore, caution should be taken in patients taking medicines that inhibit the P450 liver enzymes (e.g: azole antifungals, macrolide antibiotics, HIV protease inhibitors, calcium channel blocking agents.)

Side effects: Most adverse effects encountered with bromazepam have been referable to the central nervous system. Drowsiness, ataxia, dizziness have been most frequently reported in bromazepam use. Behaviour disorders, speech disorders, sleep disorders, confusion, headache, depression, nausea, vomiting, gastrointestinal disturbances, fatigue, numbed emotions and reduced alertness, blurred vision, seizures, agitation, dry mouth, rash, pruritus, amnesia, tremor, hypotension, tachycardia, palpitations, euphoria and decreased libido have been also reported.

Pharmaceutical precautions
Store in a cool and dry place, protected from light.

Packaging quantities
Anxio tablet: Carton containing 30 tablets in blister.

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