Tosma 1mg/5ml

Tablet
Ketotifen Fumarate (Oral)
Alco Pharma

Other Strength:
- Tosma 1mg

Alternative:
- Ketomar 1mg/5ml
- Totifen 1mg/5ml



Tosma
Description:
Ketotifen is a nonbronchodilator anti-asthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators. In addition, Ketotifen is a potent anti-allergic substance possessing a powerful and sustained noncompetitive histamine (H1) receptor blocking property.

Composition:
Tosma Tablet : Each tablet contains Ketotifen Fumarate BP equivalent to Ketotifen 1 mg.

Tosma Syrup : Each 5 ml syrup contains Ketotifen Fumarate BP equivalent to Ketotifen 1 mg.

Indication/Use:
Ketotifen is a nonbronchodilator anti-asthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators. In addition, Ketotifen is a potent anti-allergic substance possessing a powerful and sustained noncompetitive histamine (H1) receptor blocking property.

Dosage Guideline:
(Ketotifen may be taken with or without food)
Above 3 years and Adults- 1 mg twice daily (once in the morning & once in the evening), Elderly- Same as adult dose or as advised by the physician. 6 months to 3 years- 0.25 ml / kg body weight, twice daily (Once in the morning & once in the evening).
* Missed dose- If a dose of this medicine is missed that should be taken as soon as possible. However, if it is almost time for the next dose, skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled in case of a missed dose.

Side Effects:
Drowsiness, and in isolated cases dry mouth and slight dizziness may occur at the beginning of treatment but usually disappear spontaneously after a few days.

Contraindication:

Hypersensitivity to Ketotifen or any other components of the formulation.

Use in Pregnancy & Lactation
Pregnancy : Its safety in human pregnancy has not been established. Ketotifen should therefore be given to pregnant women only in compelling circumstances.
Lactation : Ketotifen is excreted in breast milk. Therefore mothers receiving Ketotifen should not breast-feed.

Drug Interaction:
A reversible fall in the thrombocyte count in patients receiving Ketotifen concomitantly with oral anti-diabetic agents has been observed in rare cases. So it has been suggested that this combination should therefore be avoided.

Over Dose:
The reported features of over dosage include confusion, drowsiness, disorientation, headache, bradycardia and respiratory depression.

Therapeutic Class:
Antiasthmatic

Dosage Form:
Tablet, Syrup

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