Tenoren 50mg

Tablet
Atenolol
ACI Pharmaceuticals

Other Strength:
- Tenoren 25mg
- Tenoren 100mg
- Tenoren Plus 50mg+25mg

Alternative:
- TENOLOC 50mg
- Cardilock 50mg



Tenoren
Description
Tenoren®is the preparation of Atenolol. It is a synthetic,β1-selective (cardioselective) adrenoreceptor blocking agent without membrane stabilizing or intrinsic sympathomimetic activity.

Indications
Tenoren®isindicated for the following conditions –-Hypertension-Angina Pectoris -Cardiac Arrhythmia-Acute Myocardial Infarction

Dosage and administration
Hypertension:The initial dose is 50mg once daily. If an optimal response is not achieved, the dose should be increased to 100mg once a day.

Angina pectoris:The initial dose is 50mg once daily. If an optimal response is not achieved within one week, the dose should be increased to 100mg once a day. Some patients may require a dose of 200mg once a day for optimal effect.

Cardiac arrhythmia:The initial dose is 25-50 mg once daily. If an optimal response is not achieved, the dose should be increased to 100mg once a day.

Acute myocardial infarction:Atenololcan be given orally 50mg twice a day or 100mg once a day after initial therapy with intravenous Atenolol (Patients who present within 12 hours of onset of chest pain, intravenous Atenolol 5mg should be injected over 5 minutes followed by another 5mg intravenous injection 10 minutes later. In patients who tolerate the full intravenous dose, e.g. 10mg, Tenoren®50mg tablet should be initiated 10 minutes after the last intravenous dose followed by another 50mg oral dose 12 hours later).

Elderly and renal impairment:
25mg once a day.

Patients on hemodialysis:25mg or 50mg after each dialysis; this should be done under hospital supervision as marked falls in blood pressure may occur.

Children and adolescents:
Safety and effectiveness in pediatric patients have not been established.

Use in pregnancy and lactation
Atenolol can cause fetal harm when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus. Caution should be exercised when Atenolol is administered to a woman, who is breast feeding.

Side-effects
In general, Atenolol is well tolerated although in a small undesired events have been reported, such as hallucinations, headache, impotence, purpura, thrombocytopenia, visual disturbance, sick sinus syndrome, dry mouth, reversible mental depression, dry eyes.

Contraindications
Atenolol is contraindicated in sinus bradycardia, heart block greater than first degree, cardiogenic shock, and overt cardiac failure. It is also contraindicated in patients with a history of hypersensitivity to Atenolol or any of the drug product's components.

Precautions
Patients already on a β1blocker must be evaluated carefully before Atenolol is administered. Initial and subsequent Atenolol dosages can be adjusted downward depending on clinical observations including pulse and blood pressure. Atenolol may aggravate peripheral arterial circulatory disorders.

Warnings
In patients who have congestive heart failure controlled by digitalis and/or diuretics, Atenolol should be administered cautiously. Continued depression of the myocardium with β-blocking agents over a period of time can, in some cases, lead to cardiac failure.

Drug Interactions
Combined use of beta-blockers and calcium channel blockers with negative inotropic effects e.g. verapamil and diltiazem can cause severe hypotension, bradycardia and cardiac failure. Digitalis glycosides, in association with beta-blockers, may increase atrio-ventricular conduction time. In addition beta-blockers have interaction with clonidine that may result in severe rebound hypertension. Concurrent administration of indomethacin reduces the antihypertensive action.

Pharmaceutical precautions
Store in cool & dry place. Protect from light.

Presentation
Tenoren®25mg Tablet: Each tablet contains Atenolol BP 25mg
Tenoren®50mg Tablet: Each tablet contains Atenolol BP 50mg
Tenoren®100mg Tablet: Each tablet contains Atenolol BP 100mg

Package quantities
Tenoren®25mg Tablet: Carton of 50 tablets in blister
Tenoren®50mg Tablet: Carton of 150 tablets in blister
Tenoren®100mg Tablet: Carton of 100 tablets in blister

এই পাতাটি ৩০৫ বার দেখা হয়েছে