Rotate 400mg

Tablet
Calcium Orotate Dihydrate
Ziska Pharmaceuticals Limited

Other Strength:
- Rotate 740mg

Alternative:
- Calorate 400mg
- Rocal-O 400mg
- Rotacal 400mg
- Carben O 400mg
- Calbostar 400mg



Rotate
Presentation
Rotate tablet: Each tablet contains Calcium Orotate Dihydrate INN equivalent to Calcium Orotate 400 mg.

Description
Rotate contains Calcium Orotate, a calcium supplement with a functional amino acid chelating ligand-orotic acid. Orotic acid assists the transport of calcium through cellular membrane structure, facilitating the intracellular uptake of calcium, particularly in bone. Calcium Orotate also helps in the maintenance of healthy cartilage. Furthermore, Orotate is involved in the synthesis of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Calcium Orotate has the ability to penetrate complex cell membrane and it can be metabolized in cartilage

Indications
1. To prevent or treat low blood calcium levels in people who do not get enough calcium from diets.
2. To fulfill the calcium deficiency or meet extra need of calcium in conditions like

Osteomalacia
Rickets
Postmenopausal osteoporosis
Senile osteoporosis
Juvenile osteoporosis
Drug induced osteoporosis
(Phenytoin, Phenobarbital, Prednisolone)
Pregnancy and lactation
Premenstrual syndrome (PMS)
Hypoparathyroidism
Hip joint plastic surgery


3. Act against a number of inflammatory diseases like

Arthritis
Multiple sclerosis
Spondylitis

4. Help in controlling weight by suppressing the habit of frequent appetite of chronic overeaters.

5. It is also beneficial in reducing the effects of mood swings.

6. Proved to be quite effective in cognitive enhancement.
7. Protect the heart by enhancing the efficiency of cardiac muscles

Dosage & Administration
As an addition to the daily diet, 2-3 tablets are usually recommended with meal or as directed by health care professional

Side Effects
Side Effects
Bloating and swelling in the abdomen are common side effects of Calcium Orotate. Constipation, nausea, vomiting, headache, increased thirst and urination, may occur in frequently

Precautions
Precaution is needed if the patient is allergic to calcium orotate. Before using this product in kidney disease, kidney stones, little or no stomach acid (achlorhydria), disease of the pancreas, a certain lung disease (sarcoidosis), difficulty absorbing nutrition from food (malabsorption syndrome) precaution is
needed

Contraindications
Rotate is contraindicated in conditions like kidney stone, kidney disease, increased activity of the parathyroid gland, high amount of calcium in urine, high amount of calcium in the blood, extreme loss of body water

Use in Pregnancy & Lactation
Women who are pregnant and breast-feeding need more calcium. Pregnancy related high blood pressure is a common and serious risk for women and their babies, and taking supplemental forms of calcium orotate can help reduce this risk

Commercial Packaging
Rotate tablet: Each box contains in 3x10’s strips.

Prescriber Information
Drug Interactions
Calcium can decrease absorption of the following drugs when taken together- biphosphonates (e.g. alendronates), quinolone antibiotics (e.g. ciprofloxacin, levofloxacin) and tetracycline antibiotics (e.g. doxycycline, minocycline), levothyroxine, phenytoin (anticonvulsant), and tiludronate disodium (to treat Paget's disease). Thiazide-type diuretics can interact with calcium supplements, increasing the risks of hypercalcemia and hypercalciuria.

এই পাতাটি ২৩৩ বার দেখা হয়েছে