ঔষধের বিস্তারিত বা বিকল্প ঔষধ জানতে ঔষধের নাম দিয়ে সার্চ দিন। যেমন- Napa বা Alatrol বা Amodis
Progut 20mg
Tablet
Esomeprazole Popular Pharmaceuticals Ltd
Other Strength:
- Progut 40mg
- Progut-N 500mg+20mg
Alternative:
- Opton 20mg
- MAXIMA 20mg
- Maxima MUPS 20mg
- Nexum 20mg
- Sergel 20mg
- Esomep 20mg
- Esopra 20mg
- Emep 20mg
- Esoz 20mg
- Esoben 20mg
- Esoben MUPS 20mg
- Esonix 20mg
- Nexum MUPS 20mg
- Maxpro 20mg
- Maxpro MUPS 20mg
Progut
Indication
ProgutTM Capsule/tablet: ProgutTMcapsule/tablet is indicated for the relief of heartburn and other symptoms associated with gastro esophageal reflux diseases (GERD) and for the healing of erosive esophagitis, a potentially serious condition associated with GERD. The FDA approved Esomeprazole is also indicated in combination with Amoxicillin and Clarithromycin, for the eradication of Helicobacter pylori infection in patients with duodenal ulcer disease.
ProgutTM IV Injection: ProgutTM IV Injection is indicated for gastric antisecretory treatment when the oral route is not possible. Such as: Bleeding peptic ulcer, Short-term treatment of GERD (Upto 10 days), Erosive Esophagitis (EE), Pre and post operative hyperacidity and Hyperacidity in patients with non-surgical NPO status.
Dosage & Administration
Dosage and Administration
Disease
Dose
Frequency
Gastroesophageal reflux disease (GERD)
Healing of erosive esophagitis
20 mg or 40 mg
Once daily for 4 to 8 weeks *
Maintenance of healing of erosive esophagitis
20 mg
Once daily *
Symptomatic gastro-esophageal reflux
20 mg
Once daily for 4 weeks *
H. pylori eradication to reduce the risk of duodenal ulcer recurrence
Triple therapy:
Esomeprazole
40 mg
Once daily for 10 days
Amoxicillin
1000 mg
Twice daily for 10 days
Clarithromycin
500 mg
Twice daily for 10 days
*Depends on the severity of the disease.
ProgutTM IV Injection: The recommended adult dose is 40 mg Esomeprazole given once daily by intravenous injection (not less than 3 minutes) or intravenous infusion (10 to 30 minutes). ProgutTM IV injection should not be administered concomitantly with any other medications through the same intravenous site.Treatment with ProgutTM IV injection should be discontinued as soon as the patient is able to resume treatment with ProgutTM delayed-release capsules. Safety and effectiveness in paediatric patients have not been established.
Method of Administration
Injection: ProgutTM IV should be given as a slow intravenous injection. The solution for IV injection is obtained by adding to the vial 5 ml of the solvent (WFI) provided. After reconstitution the injection should be given slowly over a peroid of at least 3 minutes. The solution should be used within 12 hours of reconstitution when stored at room temperature up to 30o C. No refrigeration is required. The reconstituted solution should not be used if it contains visible particulate.
Infusion: Reconstitute one sterile single dose vial of ProgutTM IV Injection with 5 ml of the solvent (WFI) provided and further diluting the resulting solution within 0.9% Sodium Chloride solution or 5% Dextrose solution to make a final volume of 50 ml. The resultant infusion should be given intravenously over a period of 10-30 minutes. Chemical and physical in-use stability has been demonstrated for 12 hours after reconstitution with 0.9% Sodium Chloride solution or for 6 hours after reconstitution with 5% Dextrose solution. From a microbial point of view, the product should be used immidiately. Any unused portion should be discarded.
Precautions
Symptomatic response to therapy with Esomeprazole does not preclude the presence of gastric malignancy. When using in combination with antibiotic, refer to the prescribing information of the respective antibiotics. Paediatric patient: Safety and effectiveness have not yet been established in paediatric patients. Geriatric: Dosage adjustment is not necessary. Renal insufficiency: Dosage adjustment is not necessary. Hepatic insufficiency: Dosage adjustment is not necessary in patients with mild to moderate liver impairment. However, in patients with severe hepatic insufficiency, a dose of 20 mg once daily of Esomeprazole should not be exceeded. Gender: No dosage adjustment is necessary. Use in pregnancy: This drug should be used during pregnancy only if clearly needed. Use in lactation: As Esomeprazole is likely to be excreted in human milk, a decision should be made whether to discontinue the drug or nursing.
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