Nitalet 500mg

Tablet
Nitazoxanide
Amulet Pharmaceuticals

Other Strength:

Alternative:
- NIDOZOX 500mg
- Nitazox 500mg
- Zox 500mg
- Alinix 500mg
- Proxa-A 500mg
- Diar 500mg
- Adnix 500mg
- Nitoxin 500mg
- Nitacure 500mg
- Xanita 500mg



Nitalet
DESCRIPTION:
Nitazoxanide, a synthetic antiprotozoal agent. Nitazoxanide is well absorbed from GIT. It interferes with the Pyruvate Ferredoxin Oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic glucose energy metabolism. This results in cell swelling, membrane damage resulting in dysfunction of the parasite.

COMPOSITION:
NITALET tablet : Each film coated tablet contains Nitazoxanide INN 500 mg.

INDICATION:
Diarrhoea caused by Cryptosporidium parvum and
Giardia lamblia.
Amebiasis and helminth infections.

DOSAGE & ADMINISTRATION:
Age >12 years : 1 tablet (500 mg) twice daily for 3 days. The tablet should be taken with food.

SIDE EFFECT:
Nitazoxanide is generally well tolerated. However abdominal pain, diarrhoea, vomiting and headache have been reported rarely.

PRECAUTION:
Nitazoxanide should be administrated with caution to patients with hepatic, renal and biliary disease.

CONTRAINDICATION:
Known hypersensitivity to Nitazoxanide or any other ingredient in the formulations.

USE IN PREGNANCY AND LACTATION :
Pregnancy category B: This drug should be used during pregnancy only if clearly needed.
Nursing mother: It is not known whether Nitazoxanide is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Nitazoxanide is administrated to a nursing women.

DRUG INTERACTION:
Nitazoxanide is highly bound to plasma protein (>99.9%). Therefore, caution should be used when administering Nitazoxanide concurrently with other highly plasma-protein bound drugs.

OVER DOSAGE:
Information on Nitazoxanide over dosage is not available. Single oral doses up to 4000 mg Nitazoxanide have been administered to healthy adults without significant adverse effects.

STORAGE:
Store in a cool and dry place, away from light and moisture. Once reconstituted suspension should be used within 7 days. Keep out of the reach of Chil dren.

HOW SUPPLIED:
NITALET tablet : Box contains 2 X 6 tablets in Alu-Alu blister pack.

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