Nitacure 500mg

Tablet
Nitazoxanide
BENHAM pharmaceuticals

Other Strength:

Alternative:
- NIDOZOX 500mg
- Nitazox 500mg
- Zox 500mg
- Alinix 500mg
- Proxa-A 500mg
- Diar 500mg
- Adnix 500mg
- Nitalet 500mg
- Nitoxin 500mg
- Xanita 500mg



Nitacure
Composition:
Nitacure tablet : Each film coated tablet contains Nitazoxanide INN 500 mg. Nitacure 30 ml suspension : Each 5 ml suspension contains Nitazoxanide INN 100 mg. Nitacure 60 ml suspension : Each 5 ml suspension contains Nitazoxanide INN 100 mg.

Description:
Nitazoxanide, a synthetic antiprotozoal agent. Nitazoxanide is well absorbed from GIT. It interferes with the Pyruvate Ferredoxin Oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic glucose energy metabolism. This results in cell swelling, membrane damage resulting in dysfunction of the parasite.

Indication:
1. Diarrhoea caused by Cryptosporidium parvum and Giardia lamblia.
2. Amebiasis and helminth infections.

Dosage & Administration:
Age 1 - 3 years : 5 ml (100 mg) twice daily for 3 days
Age 4 - 11 years: 10 ml (200 mg) twice daily for 3 days
Age >12 years : 25 ml or 1 tablet (500 mg) twice daily for 3 days
The suspension or tablet should be taken with food.

Side Effect:
Nitazoxanide is generally well tolerated. However abdominal pain, diarrhoea vomiting and headache have been reported rarely. Precaution: Nitazoxanide should be administrated with caution to patients with hepatic, renal and biliary disease.

Contraindication:
Known hypersensitivity to Nitazoxanide or any other ingredient in the formulations

Use in Pregnancy & Lactation:
Pregnancy category B:
This drug should be used during pregnancy only if clearly needed. Nursing mother: It is not known whether Nitazoxanide is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Nitazoxanide is administrated to a nursing woman.

Drug Interaction:
Nitazoxanide is highly bound to plasma protein (>99.9%). Therefore, caution should be taken when administering Nitazoxanide concurrently with other highly plasma-protein bound drugs.


Over Dosage:
Information on Nitazoxanide over dosage is not available. Single oral doses up to 4000 mg Nitazoxanide has been administered to healthy adults without significant adverse effects.

Reconstitution for Suspension:
Nitacure 30 ml suspension: Shake the bottle well before adding water. Then add 20 ml of boiled and cooled water (with the help of provided cup) into the bottle and shake well to make 30 ml suspension.
Nitacure 60 ml suspension: Shake the bottle well before adding water. Then add 40 ml of boiled and cooled water (with the help of provided cup) into the bottle and shake well to make 60 ml suspension.

Pharmaceutical Precaution:
Store in a cool and dry place, away from light and moisture. Once reconstituted suspension should be used within 7 days.

এই পাতাটি ১০১১ বার দেখা হয়েছে