Laxur 20mg+50mg

Tablet
Furosemide + Spironolactone
Healthcare Pharmaceuticals

Other Strength:

Alternative:
- EDEMIDE 20mg+50mg
- Edeloss 20mg+50mg
- Fusid® Plus 20mg+50mg
- Spirocard Plus 20mg+50mg
- Uritone 20mg+50mg



Laxur
Description
Laxur is a combination diuretic containing a loop diuretic, Frusemide and a potassium sparing diuretic, Spironolactone. Spironolactone and Frusemide have different but complementary mechanisms and sites of action. Therefore, when given together they produce synergistic or additive diuretic effects. The Frusemide component inhibits the Na+/K+/2Cl- cotransporter in the ascending Loop of Henle and blocks the reabsorption of sodium, potassium and chloride ions thereby increasing the quantity of sodium and the volume of water excreted in the urine. This characteristically induces potassium loss. The Spironolactone component inhibits the reabsorption of sodium in exchange for potassium at the distal tubule by antagonizing the action of aldosterone so that sodium excretion is greatly favored and the excess loss of potassium, induced by the Frusemide, is reduced.

Indications
Laxur® is indicated for the treatment of
Essential hypertension
Congestive heart failure
Liver cirrhosis, with collection of fluid in the abdominal cavity (ascites)
Swelling due to excess fluid retention (edema)
Overproduction of aldosterone (hyperaldosteronism)

Supply
Laxur® Tablet: Each box containing 3x10s tablets in blister pack.

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