Iverum 6mg

Tablet
Ivermectin (Oral)
Ziska Pharmaceuticals Limited

Other Strength:

Alternative:
- A-Mectin 6mg
- Parakil 6mg
- Alice 6mg
- Imec 6mg
- Veratin 6mg
- Univer 6mg
- Ivactin 6mg



Iverum
Presentation
Iverum 6 mg tablet : Each tablet contains Ivermectin USP 6 mg.

Description
Iverum (Ivermectin). is a selective anti-parasitic agent due to its high affinity for glutamate-gated chloride ion channels found in the peripheral nervous system and muscle cells of parasites. The binding of Ivermectin to this ion channel results in increased permeability of the cell membrane to chloride ions, leading to hyperpolarization with subsequent paralysis and death of the parasites. It may also impair normal intrauterine development of parasites and may inhibit their release from the uteri of gravid female parasites.

Indications
Ivermectin is used in the treatment of Scabies caused by Sarcoptes scabiei, Filariasis caused by Wuchereria bancrofti (Lymphatic filariasis). It is also used in the treatment of Pediculosis (head lice), Onchocerciasis, Strongyloidosis and Trichuriasis.

Dosage & Administration
For Scabies, Strongyloidosis & Head Lice : 200 mcg/kg
Body Weight (Kg) No. of 6 mg Tablet Duration
15-24 .50 For Scabies & Strongyloidiasis:
Single dose, if necessary to be
repeated in 7-14 days
25-35 1
36-50 1.50 For Head Lice:
3-dose regimen once daily given on
days 1, 2 & 10
51-65 2
66-79 2.50
80 and above 200 mcg/Kg

For Lymphatic Filariasis & Onchocerciasis : 150 mcg/kg
Body Weight (Kg) No. of 6 mg Tablet Duration
15-25 .50 Single dose, if necessary to be
repeated in 7-14 days
26-44 1
45-64 1.50
65-84 2
84 and above 150 mcg/Kg

Iverum 6 (Ivermectin) should be administered as a single dose with a full glass (240 ml) of water on an empty stomach (1 hour before breakfast).

Side Effects
Common side effects are nausea, vomiting or decreased appetite, diarrhoea or constipation, muscle or joint pain, swelling of the lymph nodes, fever, tiredness, dizziness, tremor, itching, eye lid swelling or eye redness.

Precautions
Stop taking Ivermectin and seek emergency medical attention if you experience symptoms of a rare but serious allergic reaction including swelling of the lips, tongue or face.

Contraindications
It is contraindicated in bronchial asthma. It is also contraindicated in patients who are hypersensitive to any component of this product.

Use in Pregnancy & Lactation
Safety and efficacy have not been established for pregnant or lactating women.

Commercial Packaging
Iverum 6 mg tablet: Each box contains 1X10's tablets in blister pack

Storage after reconstitution
Do not store above 25°C. Keep in a dry place & protected from light. Keep out of reach of Children.

Drug Interaction
Concomitant use of Ivermectin with Diazepam and related Tranquilizers as well as any Monoamine Oxidase (MAO) inhibitors exaggerated the sedation and adverse neurologic effects

Children and Adolescent
Safety and efficacy have not been established for children less than 15 kg or below 5 years.

Storage
Do not store above 25°C. Keep in a dry place & protected from light. Keep out of reach of Children.


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