Fluver 5mg

Tablet
Flunarizine
ACI Pharmaceuticals

Other Strength:
- Fluver 10mg

Alternative:
- Flurizin® 5mg
- Vertig 5mg
- Fluzin 5mg



Fluver
Presentation
Fluver®5mg Tablet: Each tablet contains Flunarizine5mg as Hydrochloride BP.Fluver®10mg Tablet: Each tablet contains Flunarizine10mg as Hydrochloride BP.

Uses
Fluver®is indicated for-prophylaxis of classic (with aura) or common (without aura) migraine-symptomatic treatment of vestibular vertigo owing to a diagnosed functional disorder of the vestibular system-symptomatic treatment of dizziness, tinnitus, vertigo and headache owing to cerebral ischemia-symptomatic treatment of intermittent claudication,Raynaud’s phenomenon, paresthesiae, cold extremities, nocturnal cramp, and trophic disorders owing to ischemia ofthelimbs-as add-on therapy to existing anticonvulsant medication in the refractory seizures

Dosage & administration
Migraine: The recommended dose of Fluver®for migraine prophylaxis is 10mg orally once daily in adults and 5-10mg once daily in children. If a patient responds satisfactorily to the starting dose and if a maintenance treatment is required, the dose of Fluver®should be decreased so that each week the patient has 5 days of treatment at the same daily dose of Fluver®and 2 successive drug-free days. Even if the prophylactic treatment is successful and well tolerated it should be interrupted after 6 months and reinitiated only if migraine relapses.Vertigo and peripheral vascular disease:For vertigo, peripheral vascular disease and refractory epilepsy, treatment with Fluver®is started with 10mg dose at bedtime for patients younger than 65 years of age and with 5mg dose at bedtime for patients older than 65 years. For vertigo dosage should be increased up to 20mg three times daily and for refractory epilepsy it should be increased up to 100mg daily with themaintenance dose targeted to produce serum levels of 60 g/litre.

Contra-indications, warning, etc.
Contra-indications:Flunarizine is contraindicated in patients with hypersensitivity to Flunarizine or Cinnarizine, depressive illness, Parkinson’s disease or extra pyramidal disorders.Pregnancy:The safely of Flunarizine for use in pregnancy has not been established.Lactation:No data is available on the excretion of Flunarizine in human breast milk. Breast feeding should therefore be avoided in women taking Flunarizine.Patients with hepatic disease: Since Flunarizine is primarily metabolized in the liver, dosage adjustment is required in hepatic insufficiency.Precautions: Discontinue therapy if fatigue increases progressively.Drug interactions: Alcohol, hypnotics or tranquilizers may interact with Flunarizine.Side effects: Drowsiness or fatigue, weight gain, increased appetite, depression and extra pyramidal symptoms may occur.

Pharmaceutical precautions
Store in a cool&dry place. Protect from light.

Package quantities
Fluver®5mgTablets:
Fluver®10mgTablets:
Carton of 100 tablets in blister
Carton of 80 tablets in blister

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