Ecox 120mg

Tablet
Etoricoxib
Alco Pharma

Other Strength:
- Ecox 60mg
- Ecox 80mg
- Recox 120mg

Alternative:
- Tory 120mg
- Cox-E 120mg
- Vericox 120mg
- Riox 120mg
- Coxetori 120mg
- Etovan 120mg
- Etoben 120mg
- Aroxia 120mg
- Setorib 120mg
- Ribox 120mg
- Recox 120mg



Ecox
Description:
Ecox (Etoricoxib) is a Non-Steroidal Anti-Inflammatory Drug (NSAID) that exhibits anti-inflammatory, analgesic and antipyretic activities. It is a potent, orally active, highly selective cyclooxygenase-2 (COX-2) inhibitor within and above the clinical dose range. COX-2 has been shown to be primarily responsible for the synthesis of prostanoid mediators of pain, inflammation and fever. Selective inhibition of COX-2 by Etoricoxib decreases these clinical signs and symptoms with decreased GI toxicity and without effects on platelet function.

Composition:
Ecox 60 Tablet : Each film-coated tablet contains Etoricoxib INN 60 mg.
Ecox 90 Tablet : Each film-coated tablet contains Etoricoxib INN 90 mg.
Ecox 120 Tablet : Each film-coated tablet contains Etoricoxib INN 120 mg.

Indication/Use:
Ecox (Etoricoxib) is indicated for relief of pain and inflammation in -
·
Osteoarthritis,
·
Rheumatoid arthritis,
·
Other chronic musculoskeletal disorders,
·
Acute gout,
·
Dysmenorrhoea, &
·
Following dental surgery.

Dosage Guideline:
Adult and adolescent over 16 years:
·
Osteoarthritis, chronic musculoskeletal disorders & dysmenorrhoea: 60 mg, once daily.
·
Rheumatoid arthritis: 90 mg, once daily.
·
Pain following dental surgery & acute gout: 120 mg, once daily.
Safety and effectiveness of Etoricoxib in paediatric patients have not been established.

Side Effects:
Dry mouth, taste disturbance, mouth ulcers, flatulence, constipation, appetite and weight changes, chest pain, fatigue, paraesthesia, influenza-like syndrome & myalgia.

Contraindication:
Hypersensitivity to any component of this product, severe hepatic impairment, inflammatory bowel disease, congestive heart failure, peripheral artery disease, established ischemia, uncontrolled hypertension (persistently above 140/90 mmHg) & breast-feeding mother.

Drug Interaction:
Oral anticoagulants, diuretics and ACE inhibitors, Acetylsalicylic acid, Cyclosporin and Tacrolimus, Lithium, Methotrexate, oral contraceptives, Prednisone/Prednisolone, Digoxin, drugs metabolized by sulfotransferases (Ethinyl Estradiol), drugs metabolized by CYP isoenzymes, Ketoconazole, Rifampicin, and Antacids have interaction with Etoricoxib.

Use in Pregnancy & Lactation:
As with other drugs known to inhibit prostaglandin synthesis, use of it should be avoided in late pregnancy because it may cause premature closure of the ductus arteriosus. It should be used during the first two trimesters of pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk.

Therapeutic Class:
NSAID

Dosage Form:
Tablet

Storage:
Store at a cool & dry place protected from light & moisture. Keep out of reach of children.




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