Dompi 10mg

Tablet
Domperidone Maleate
Alco Pharma

Other Strength:

Alternative:
- Omidon 10mg
- Motifast 10mg
- Motigut 10mg
- Gutset 10mg
- Domilux 10mg
- Vave 10mg
- Domidon 10mg
- Veridom 10mg
- Dysnov 10mg
- Apuldon 10mg
- Benidon 10mg
- Domiren 10mg



Dompi
Description:
Dompi (Domperidone) is a Dopamine antagonist .Because it does not readily enter the central nervous system, its effects are confined to the periphery and acts principally at the receptor in the chemoreceptor trigger zone.

Composition:
Dompi Tablet: Each film coated tablet contains Domperidone Maleate BP equivalent to 10 mg Domperidone.

Indication/Use:
1. Stimulation of gut mobility
a) Non-ulcer dyspepsia
b) Esophageal reflux, reflux esophagitis and gastritis
c) Diabetic gastroparesis
d) Functional dyspepsia
2. Prevention and symptomatic relief of acute nausea and vomiting from any cause
including cytotoxic therapy, radio therapy and anti-parkinsonism therapy
3. In the treatment of migraine.

Dosage Guideline:
The recommended oral dose for
Adults : 10 - 20 mg every 4 - 8 hours daily
Children : 0.2 - 0.4 mg/kg every 4 - 8 hours daily.
Note : Dompi tablet and suspension should be taken 15 - 30 minutes before a meal.
For acute nausea and vomiting, maximum period of treatment is 12 weeks.

Side Effects:
Domperidone may produce hyperprolactinemia(1.3% frequency). This may result in galactorrhea, breast enlargement and soreness and reduced libido. Dry mouth (1.9%), thirst, headache (1.2%), nervousness, drowsiness (0.4%), diarrhea (0.2%), skin rash and itching (0.1%) may occur during treatment with Domperidome. Extra-pyramidal reactions are seen in 0.05% of patients in clinical studies.

Contraindication:
Domperidone is contraindicated to patients who have known hypersensitivity to this drug and in case of neonates.

Drug Interaction:
Domperidone may reduce the hypoprolactinemic effect of bromocriptine. The action of Domperidone on GI function may be antagonized by anti-muscarinics and opioid analgesics.

Use in Pregnancy & Lactation:
Pregnant women : The safety of Domperidone has not been proven and it is therefore not recommended during pregnancy.Animal studies have not demonstrated teratogenic effects on the fetus.
Lactating mother : Domperidone may precipitate galactorrhea and improve post-natal lactation. It is secreted in breast milk but in very small quantities insufficient to be considered harmful.

Therapeutic Class:
Gastroprokinetic Agent

Dosage Form:
Tablet, Suspension.

Storage:
Store in a cool and dry place, protected from light and moisture.



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