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Caldical-D 500mg+200IU

Tablet
Calcium Carbonate [Elemental] + Vitamin D3
Ziska Pharmaceuticals Limited

Other Strength:

Alternative:
- Aristocal D 500mg+200IU
- Calbo-D 500mg+200IU
- Calcium A & D 500mg+200IU
- Ultracal-D 500mg+200IU
- Acical-D 500mg+200IU
- Nutribon 500mg+200IU
- Bonwell-D 500mg+200IU
- Calmi-D 500mg+200IU
- Adcal D 500mg+200IU
- Calcibo D 500mg+200IU
- Carben D 500mg+200IU
- Calcin-D 500mg+200IU



Caldical-D
Presentation
Caldical-D Tablet: Each film coated tablet contains Calcium Carbonate USP 1250 mg (equivalent to 500 mg of elemental Calcium) & Vitamin D3 BP 200 IU

Description
Caldical-D is a combination of Calcium & Vitamin D3. Calcium is needed for the formation of strong bones and healthy teeth and is involved in helping the blood to clot.It is also required to transmit nerve signals and help muscles to work. Vitamin D3 improves the absorption of Calcium into the body

Indications
Caldical-Dis indicated in

Treatment of osteoporosis, rickets, osteomalacia, tetany andparathyroid disease.
In pregnancy & lactation due to increased demand
In kidney disease and pancreatitis
During therapy with anti-seizure medications.
The prevention & treatment of Calcium or Vitamin D deficiency
specially in the housebound and institutional elderly patients.

Dosage & Administration
Adults, elderly and children above 12 years of age: 2 tablets per day, preferably one tablet in the morning and one tablet in the evening

Side Effects
The use of calcium supplements has rarely given rise to mild gastro-intestinal
disturbances, such as constipation, flatulence, nausea, gastric pain, diarrhoea.
Following administration of Vitamin D supplements occasional skin rash has been
reported. Hypercalcuria, and in rare cases hypercalcaemia have been seen with long
term treatment at high dosages.

Precautions
Patients with mild to moderate renal failure (commonly found in the elderly) mild
hypercalcuria should be supervised carefully with periodic checks of urinary calcium
excretion and plasma calcium levels.Urinary calcium excretion should also be measured in patients with a history of renal stones to exclude hypercalcuria.

Contraindications
Hypersensitivity to any component of the product. Hypercalcaemia for example, as a result of hyperparathyroidism, Vitamin D overdose, decalcifying tumours such as myeloma, bone metastases or sarcoidosis, severe hypercalciuria, renal stones, osteoporosis due to immobilization

Use in Pregnancy & Lactation
Normal requirements of Calcium & Vitamin D are raised during pregnancy & lactation. Calcium is excreted in breast milk but not sufficiently to produce adverse effect in theinfant. During pregnancy & lactation therapy should be under medical supervision.

Commercial Packaging
Caldical-D Tablet:Each box contains 5x10's tablets in blister strip

Drug Interaction


The risk of hypercalcaemia should be considered in patients taking thiazide diureticssince these drugs can reduce urinary calcium excretion. Certain foods (e.g. those containing oxalic acid, phosphate or phytinic) may reduce the absorption of Calcium.
Concomitant treatment with phenytoin or barbiturates can decrease the effect of


Vitamin D because of metabolic activation. Concomitant use of glucocorticoids can decrease the effect of Vitamin D. The effects of digitalis and other cardiac glycosidesmay be accentuated with the oral administration of Calcium combined with Vitamin D.
Calcium salts may reduce the absorption of thyroxine, biphosphonates, sodium
fluoride, quinolone or tetracycline antibiotics or iron. It is advisable to allow a minimum period of four hours before taking the Calcium.

Overdose
The most serious consequence of acute or chronic overdose is hypercalcaemia due to Vitamin D toxicity. Symptoms include nausea, vomiting, polyuria and constipation. Chronic overdoses can lead to vascular and organ calcification as a result of hypercalcaemia.

Pediatric use
Children under 12 years of age should not take this preparation.

Storage
Store in a cool and dry place, protected from light. Keep out of reach of children.

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