SMR 10mg

Tablet
Baclofen
Amulet Pharmaceuticals

Other Strength:

Alternative:
- Lospan 10mg
- Flexilax® 10mg
- Myorel 10mg
- Mylofen 10mg
- Liorel 10mg
- Baclomax 10mg
- Spakem 10mg
- Zerolent 10mg
- Beclovan 10mg
- Baclodol 10mg
- Bacben 10mg
- Relofen 10mg
- Maxolax 10mg



SMR
DESCRIPTION
SMR is an effective muscle relaxant and antispastic agent with a spinal site of action. It exerts its action by inhibiting both monosynaptic and polysynaptic transmission in the spinal cord by stimulating GABA receptors.

COMPOSITION
SMR Tablet: Each film coated tablet contains Baclofen BP 10 mg.

INDICATION
SMR is indicated for the alleviation of spasticity resulting from multiple sclerosis particularly for the relief of flexor spasm and concomitant pain, clonus and muscular rigidity, spinal cord diseases, muscle spasm of cerebral origin especially infantile cerebral palsy, stroke or neoplastic or degenerative brain diseases. It may be of some value in patients with trigeminal neuralgia, tardive dyskinesia, cluster headache and tension type headache.

DOSAGE AND ADMINISTRATION
Muscle relaxant & spasticity: For adults: Initially 5 mg three times daily for 3 days; then 10 mg three times daily for 3 days, 15 mg three times daily for 3 days and 20 mg three times daily. Additional increases in dose may be required but should not exceed 20 mg four times daily. Maximum daily dose for spasticity should not exceed 260 mg.
For children (treatment of spasticity): Initially 1.0-1.5 mg/kg/day in 3 divided doses. Titrate to a maximum of 40 mg/day if less than 8 years of age and to a maximum of 80 mg/day if more than 8 years of age.
Trigeminal neuralgia: 50-60 mg daily in divided doses.
Tardive dyskinesia: 40 mg daily in divided doses combination with neuroleptics.

CONTRAINDICATION
SMR is contraindicated in patients who are hypersensitive to any component of this preparation.

PRECAUTION
Hallucinations and seizures may occur on abrupt withdrawal of SMR. Therefore, except for serious adverse reactions, the dose should be reduced slowly when the drug is discontinued.

SIDE EFFECT
SMR may cause drowsiness, weakness, dizziness, headache, seizures, nausea, vomiting, low blood pressure, constipation etc.

DRUG INTERACTION
The central nervous system depressant effects of SMR may be additive to those of alcohol and other CNS depressants.

USE IN PREGNANCY AND LACTATION
Pregnancy: There are no adequate and well-controlled studies in pregnant women. So, SMR should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known whether this drug is excreted in human milk. Caution should be exercised when SMR is administered to lactating mother.

STORAGE CONDITION
Store in a cool and dry place below and away from light. Keep out of the reach of children.

HOW SUPPLIED
SMR Tablet: Box Containing 30’s tablet in Alu-PVC blister pack.

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