Mokast 10mg

Tablet
Montelukast Sodium
Alco Pharma

Other Strength:
- Mokast 4mg

Alternative:
- Monocast 10mg
- Mirapro 10mg
- Montene 10mg
- Aeron 10mg
- M-Lucas 10mg
- Reversair 10mg
- Monalast 10mg
- Asmatab 10mg
- Provair 10mg
- Ventilast 10mg
- Montilet 10mg
- Montril 10mg
- Monteluk 10mg
- Mon 10mg
- Monas 10mg
- Odmon 10mg



Mokast
Description:
Mokast is a preparation of Montelukast.It is a selective and orally activeleukotriene receptor antagonist that inhibits the cysteinyl leukotriene (CysLT1) receptor. CysteinylLeukotrienes have been correlated with the pathophysiology of asthma and allergic rhinitis. CysteinylLeukotrienes may cause airway edema, smooth muscle contraction and cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of asthma. By blocking leukotrienes to bind with CysLT1 receptor Montelukast improves asthma symptoms, helps control asthma and improves seasonal allergy symptoms.

Composition:
·
Mokast 10 mg Tablet: Each tablet contains Montelukast 10 mg as Sodium INN.
·
Mokast 4 mg Chewable Tablet : Each orodispersible tablet contains Montelukast 10 mg as Sodium INN.

Indication/Use:
·
Mokast is indicated for the prophylaxis and chronic treatment of asthma in adults and paediatric patients 12 months of age and older.
·
Mokast is indicated for the relief of symptoms of seasonal allergic rhinitis in adults and paediatric patients 2 years of age and older.

Monocast is indicated for the relief of symptoms of seasonal allergic rhinitis in adults and paediatric patients 2 years of age and older.

Dosage Guideline:
Mokast is indicated for the prophylaxis and chronic treatment of asthma in adults and paediatric patients 12 months of age and older.
Mokast is indicated for the relief of symptoms of seasonal allergic rhinitis in adults and paediatric patients 2 years of age and older.
Monocast is indicated for the relief of symptoms of seasonal allergic rhinitis in adults and paediatric patients 2 years of age and older.

Side Effects:
Generally Montelukast is well tolerated. Side effects include abdominal pain, stomach or intestinal upset, fever, tiredness, dizziness, cough, dental pain, flu, stuffy nose, rash and upper respiratory tract infection.

Contraindication:
Hypersensitivity to any component of this product.

Drug Interaction:
Montelukast may be administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma and in the treatment of allergic rhinitis. In drug- interactions studies, the recommended clinical dose of Montelukast did not have clinically important effects on the pharmacokinetics of the following drugs: Theophylline, Prednisone, Prednisolone, Oral Contraceptives, Terfenadine, Digoxin, and Warfarin. The area under the plasma concentration-time curve (AUC) for Montelukast was decreased approximately 40% in subjects with co-administration of Phenobarbital. No dosage adjustment for Montelukast is recommended. It is reasonable to employ appropriate clinical monitoring when potent cytochrome P450 enzyme inducers, such as Phenobarbital or Rifampin are co-administered with Montelukast.

Use in Pregnancy & Lactation:
There are no adequate and well controlled studies of Montelukast in pregnant women. As animal reproductive studies are not always predictive of human response, Montelukast should be used in pregnancy only if clearly needed. It is not known if Montelukast is excreted in human milk. As many drugs are excreted in human milk, caution should be exercised when Montelukast is given to a nursing mother.

Over Dose:
There were no adverse experiences in the majority of overdosage reports. The most frequently occurring adverse experiences were consistent with the safety profile of Montelukast and included abdominal pain, somnolence, thirst, headache, vomiting and psychomotor hyperactivity.

Precaution:
Montelukast is not indicated for use in the reversal of bronchospasm in acute asthma attack, status asthmaticus. Therapy with Montelukast can be continued in the acute exacerbations of asthma. While the dose of inhaled corticosteroid may be reduced gradually under medical supervision, Montelukast should not be abruptly substituted for inhaled or oral corticosteroids. Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Montelukast.

Therapeutic Class:
Antiasthmatic

Dosage Form:
Tablet

Storage:
Store in a cool & dry place. Protect from light.


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