Famicef 1.5gm/vial

IV Injection
Cefuroxime Axetil
ACME Laboratories Ltd

Other Strength:
- FAMICEF 250mg
- Famicef 750mg
- Famicef 125mg/5ml
- Famicef 500mg

Alternative:
- Turbocef 1.5gm/vial
- Kilbac 1.5gm/vial
- Furotil 1.5gm/vial
- Cefotil 1.5gm/vial



Famicef
Composition : Famicef® 250 Tablet : Cefuroxime Axetil USP 250 mg.

Famicef® 500 Tablet : Cefuroxime Axetil USP 500 mg.

Famicef® Powder for Suspension : Cefuroxime Axetil USP 125 mg /5 ml.

Famicef® 750 mg IM / IV Injection : Cefuroxime Sodium USP sterile powder equivalent to Cefuroxime 750 mg / vial.

Famicef® 1.5 g IV injection : Cefuroxime Sodium USP sterile powder equivalent to Cefuroxime 1.5 g / vial.

Indications : ♦ Upper respiratory tract infections: Ear, nose and throat infections such as otitis media, sinusitis, tonsillitis and pharyngitis ♦Lower respiratory tract infection : Acute bronchitis, acute exacerbations of chronic bronchitis and pneumonia ♦Skin and soft tissue infections : Furunculosis, pyoderma and impetigo ♦ Genito-urinary tract infections: Pyelonephritis, urethritis and cystitis ♦ Multi drug resistant typhoid fever ♦ Gonorrhoea : Acute uncomplicated gonococcal urethritis and cervicitis ♦Early Lyme Disease and subsequent prevention of late Lyme Disease.

Dosage & Administration :

Infection


Dosage


Duration

Adolescents and Adults (13 years and older)

Pharyngitis / tonsillitis


250 mg b.i.d.


10 days

Acute bacterial maxillary sinusitis


250 mg b.i.d.


10 days

Acute bacterial exacerbations of chronic bronchitis


250 or 500 mg b.i.d.


10 days

Secondary bacterial infections of acute bronchitis


250 or 500 mg b.i.d.


5 - 10 days

Uncomplicated skin and skin-structure infections


250 or 500 mg b.i.d.


10 days

Uncomplicated urinary tract infections


125 or 250 mg b.i.d.


7 - 10 days

Uncomplicated gonorrhoea


1,000 mg once


Single dose

Early Lyme Disease


500 mg b.i.d


20 days

Pediatric Patients (who can swallow tablets whole)

Acute otitis media


250 mg b.i.d.


10 days

Acute bacterial maxillary sinusitis


250 mg b.i.d.


10 days

Infection


Dosage (divided b.i.d.)


Maximum Dose


Duration

Pediatric Patients (3 months to 12 years)

Pharyngitis / tonsillitis


20 mg/kg/day


500 mg


10 days

Acute otitis media


30 mg/kg/day


1,000 mg


10 days

Acute bacterial maxillary sinusitis


30 mg/kg/day


1,000 mg


10 days

Impetigo


30 mg/kg/day


1,000 mg


10 days


Injection : Adult : 750 mg three times daily by IM / IV injection.

Infants and Children : 30 - 100 mg / kg /day given in 3 or 4 equally divided doses. A dose of 60 mg / kg /day is appropriate for most infections.

Neonate : 30 - 100 mg / kg / day given in 2 or 3 equally divided doses.

Surgical prophylaxis : 1.5 gm by IV injection at induction of anaesthesia. Thereafter, give 750 mg IM / IV every 8 hours when the procedure is prolonged.

Sequential therapy in adults : Pneumonia : 1.5 gm IV injection three times or twice daily for 2 - 3 days, followed by 500 mg twice daily (oral) for 7 - 10 days. Acute exacerbation's of chronic bronchitis : 750 mg three times or twice daily (IM / IV injection) for 2 - 3 days, followed by 500 mg twice daily (oral) for 5 - 10 days. (Duration of both parenteral and oral therapy is determined by the severity of the infections and the clinical status of the patient).

Other recommendations : In Gonorrhoea : Adults : 1.5 gm as a single dose (as 2 X 750 mg injections given intramuscularly with different sites, e.g. each buttock). In Meningitis : Adults : 3 gm IV injection three times daily.

Children (above 3 months of age) : 200 - 240 mg / kg /day by IV injection in 3 or 4 divided doses reduced to 100 mg / kg / day after 3 days or on clinical improvement.

Neonates : 100 mg / kg / day by IV injection reduced to 50 mg / kg / day.

In bone and joint infections : Adults : 1.5 gm injection 3 times daily.

Children (above 3 months of age) : 150 mg / kg / day (not to exceed the maximum adult dose) in equally divided doses every 8 hours.

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