Adafil 20mg

Tablet
Tadalafil
Beximco Pharmaceuticals Ltd

Other Strength:
- Tadafil 5mg
- Tadafil 10mg

Alternative:
- Intimate® 20mg
- Nirvana 20mg
- Ciaton 20mg
- Edysta 20mg
- Viev 20mg
- Megafil 20mg



Adafil
1. What Adafil® is and what it is used for?
Adafil® (Tadalafil) tablet is an oral treatment for erectile dysfunction, is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Tadalafil has the empirical formula C22H19N3O4 representing a molecular weight of 389.41. It is available as film coated tablets for oral administration.

2. Before you take Adafil®
Before using this drug, patient should disclose to the physician the medical history, including any allergies (especially drug allergies), any penis conditions such as fibrosis/scarring, history of painful/prolonged erection (priapism), sickle cell anemia, blood system cancers (such as leukemia or myeloma), or Peyronie's disease, eye problems (retina diseases). kidney or liver disease, bleeding disorders or active stomach ulcers, heart diseases, stroke or severe high or low blood pressure. Limit alcohol intake, as it may aggravate side effects of this drug.

To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. The elderly may be more sensitive to the side effects of this drug; therefore caution is advised in this group. There have been rare reports of prolonged erections greater than 4 hours and priapism (painful erections greater than 6 hours in duration) for this class of compounds. Priapism, if not treated promptly, can result in irreversible damage to the erectile tissue. Patients who have an erection lasting greater than 4 hours, whether painful or not, should seek emergency medical attention.

3. How to take Adafil®
How much to take
The recommended starting dose of Tadalafil in most patients is 10 mg, taken prior to anticipated sexual activity (20 minutes before). The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability. The maximum recommended dosing frequency is once per day in most patients. Tadalafil may be taken without regard to food.
In case of mild renal insufficiency, no dose adjustment is required. For patients with moderate (Creatinine clearance 31 to 50 mL/min) renal insufficiency, a starting dose of 5 mg not more than once daily is recommended, and the maximum dose should be limited to 10 mg not more than once in every 48 hours. For patients with severe (creatinine clearance <30 ml/min) renal insufficiency on hemodialysis, the maximum recommended dose is 5 mg.

If you forget to take Adafil®
If you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose

If you stop taking Adafil®
Do not stop taking this medicine without talking to your doctor. You should not stop taking Adafil® just because you feel better. This is because the problem may come back or get worse again.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
Tadalafil was administered to over 5700 men (mean age 59, range 19 to 87 years) during clinical trials worldwide. Over 1000 patients were treated for 1 year or longer and over 1300 patients were treated for 6 months or more. In placebo-controlled Phase-3 clinical trials, the discontinuation rate due to adverse events in patients treated with Tadalafil 10 or 20 mg was 3.1%, compared to 1.4% in placebo-treated patients. When Tadalafil was taken as recommended in the Placebo-controlled clinical trials, the following adverse events were reported.

Tell your doctor if any of the side effects gets serious or lasts longer than a few days, or if you notice any side effects not listed in this leaflet.

5. How to store Adafil®
Keep in a cool & dry place, protected from light. Keep out of the reach of children.

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