Acitrin 10mg

Tablet
Cetirizine Hydrochloride [Oral]
ACI Pharmaceuticals

Other Strength:

Alternative:
- Atrizin 10mg
- CETIZIN 10mg
- Alatrol 10mg
- Cirizin 10mg
- Noler 10mg
- Setir 10mg
- Rhinil 10mg
- Cetriz 10mg
- Cetriben 10mg



Acitrin
Description
Acitrin®is a preparation of Cetirizine dihydrochloride. It is a piperazine derivative and metabolite of Hydroxyzine,which is long acting and has some mast-cellstabilizing activity. Principal actions of Cetirizine aremediated by selective inhibition of peripheral H1-receptors.

Indications
Acitrin®is indicated for the symptomatictreatment ofSeasonal Allergic Rhinitis such as sneezing, rhinorrhea, pruritus,ocular pruritus, tearing and redness of the eyes.Perennial Allergic Rhinitis sneezing, rhinorrhea, post-nasal discharge, nasal pruritus, ocular pruritus and tearing.Chronic Idiopathic Urticariasuch asuncomplicated skin manifestations, severity and duration of hives,pruritusandallergen induced asthma.

Dosage and administration
Adults and children aged 6 years and overAcitrin®Tablet10 mg once daily or 5 mg twice daily.Acitrin®Syrup: 2teaspoonfuls once daily or 1 teaspoonful twice daily.In patients with decreased renal function (creatinine clearance 11-31 mL/min), patients on hemodialysis (creatinine clearance less than 7 mL/min) and in hepatically impaired patients, a dose of 1/2 tablet or 1 teaspoonful once daily is recommended.

Children aged 2 to 6yearsAcitrin®Tablet: 5mg once daily or 2.5 mg twice dailyAcitrin®Syrup: 1 teaspoonful once daily or 1/2 teaspoonful twice daily.Children aged 6 months to <2 yearsAcitrin®Syrup: 1/2 teaspoonful once daily, increased to a maximum of 1/2 teaspoonful twice dailyAcitrin®Paediatric Drops: 1mlonce daily, increased to a maximum of 1ml twice daily.

Use in Pregnancy & Lactation
Cetirizine dihydrochlorideis pregnancy category B.There are no adequate and well controlled studies in pregnant women.Cetirizine should be used during pregnancy only if clearly needed. Cetirizine has been reported to be excreted inhuman breast milk. As large amount ofdrugs are excreted in human milk, use of Cetirizine in nursing mother is not recommended.

Side effects
Cetirizine dihydrochlorideis well tolerated. Lowerincidence of sedation, headache, dry mouth, and gastrointestinal disturbancesmay occur.It does not produce anticholinergic effects.

Contraindications
Cetirizine Dihydrochlorideis contraindicated in those patients with a known hypersensitivity to itor any of its ingredients orhydroxyzine.

Precautions
Could be exercised when driving a car or operating potentially dangerous machinery. Concurrent use of Cetirizine with alcohol or other CNS depressants should be avoided
because additional reductions in alertness and additional impairment of CNS performance may occur.

Drug Interactions
No clinically significant drug interactions have been found with theophylline at a low dose, azithromycin, pseudoephedrine, ketoconazole, or erythromycin.

Storage Instruction
Storeina cool and dry place, protectfrom light.

Presentation:
Acitrin®Tablet: Eachtabletcontains Cetirizine Dihydrochloride BP 10 mg
Acitrin®Syrup: Each 5 ml syrup contains Cetirizine Dihydrochloride BP 5 mg
Acitrin®Paediatric Drops: Each ml contains Cetirizine Dihydrochloride BP 2.5 mg

Package quantities
Acitrin®Tablet: Carton of 100 tablets in blister
Acitrin®Syrup: Bottle of60 ml
Acitrin®Paediatric Drops: Bottle of 15 ml with food grade dropper

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