Acical-C 1000mg+327mg+500mg

Tablet
Calcium Lactate Gluconate + Calcium Carbonate + Vitamin-C
ACI Pharmaceuticals

Other Strength:

Alternative:
- Cavic C 1000mg+327mg+500mg
- Calbo-C 1000mg+327mg+500mg
- Sante 1000mg+327mg+500mg
- Ultracal-C 1000mg+327mg+500mg
- C-4 1000mg+327mg+500mg
- Carben C 1000mg+327mg+500mg
- Calcefer 1000mg+327mg+500mg



Acical-C
Product Information:
Acical-C®is a preparation of Calcium and Vitamin C. Calcium is the most abundant mineral in the human body which is needed for muscle contraction, blood vessel contraction and expansion, the secretion of hormones and enzymes and sending message through the nervous system. Vitamin C (ascorbic acid) is a water soluble vitamin, which is very essential as human body cannot synthesize it. Vitamin C is a significant factor in the defense mechanism of the organism against infections (cold and influenza). It stimulates the immune system to produce immune substances (immunoglobulins, interferons). Vitamin C is associated with the formation of connective tissue (collagen) and intercellular material, and is therefore indispensable in the healing of wounds and bone fractures. It binds harmful substances within the body (free radicals) and thus protects cells from ageing.

Indications
Acical-C®is indicated in Increased demand for Calcium and Vitamin C in pregnancy, lactation and periods of rapid growth in children as well as in old age Prevention and treatment of Calcium and Vitamin C deficiencyMaintaining strong bones and teethInfectious disease and convalescencePremenstrual syndromeAdjuvant therapy for bone fracture, wounds, osteoporosis as well as colds and influenza

Dosage and administration
Dissolve the Acical-C®effervescent tablet in a glass of water. Adults & children of school age:1 effervescent tablet dailyChildren 3 to 7 years:½ effervescent tablet dailyInfants:As directed by the physician

Use in pregnancy & lactation
Oral Calcium supplements are recommended worldwide during pregnancy and lactation. Besides, Vitamin Cis also considered safe for pregnant and breastfeeding mothers.

Precautions
In mild hypercalciuria (exceeding 300 mg = 7.5 mmol/24 hours) as well as in chronic renal failure, or where there is evidence of stone formation in the urinary tract, adequate checks must be kept on urinary calcium excretion. If necessary, the dosage should be reduced or therapy discontinued. High doses of Vitamin D and derivatives should also be avoided with this preparation unless specially indicated. Since, Vitamin C enhances aluminium absorption, it should be taken with caution in patients with severe renal impairment, especially those receiving aluminium containing
preparations. Besides, in case of diabetic patients, the sugar content should be considered.

Side effects
Mild gastrointestinal disturbances (bloating, diarrhoea) can occur, but it is rare. In predisposed patients, prolonged treatment with high doses may promote formation of urinary calculi in urinary tract.

Contraindications
It is contraindicated in patients with hypersensitivity to drug and any of its ingredients. It is also contraindicated in case of hypercalcemia, severe hypercalciuria, severe renal failure, patients with hyperoxalauria, glucose-6-phosphatedehydrogenase deficiency, or iron overload.

Drug interactions
Calcium reduces absorption of fluoroquinolones, levothyroxine, tetracycline, tiludronate, and phenytoin. It may decrease levels of the drug digoxin. Thiazide, and diuretics similar to thiazide, can interact with Calcium to increase the chances of developing hypercalcemia and hypercalciuria. Aluminum and magnesium antacids can both increase urinary calcium excretion. Prednisone can cause Calcium depletion and eventually osteoporosis, when used for more than a few weeks. Vitamin C enhances iron absorption and it may interfere with urinary glucose determination.

Overdose
Acute overdosehas not been reported. It may cause gastrointestinal disturbances but not hypercalcemia, except in patients who are taking high dosage of Vitamin D and derivatives.

Pharmaceutical precautions
Should be stored in a cool and dry place. Protect from light and moisture and keep out of reach of children.

Presentations
Acical-C®: Each effervescent tablet contains Calcium Lactate Gluconate BP1000 mgCalcium Carbonate BP 327 mgAscorbic Acid BP 500 mg

Package quantities
Acical-C®: Each tube contains 10 effervescent tablets

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