Eperisone Hydrochloride

Indications
Improvement of muscular hypertonic symptoms in the following diseases: Cervical syndrome, periarthritis of the shoulder, lumbago.
Spastic paralysis in the following disease: Cerebrovascular disease, spastic spinal paralysis, cervical spondylosis, postoperative sequelae (including cerebrospinal tumor), sequelae to trauma (spinal trauma, head injury), amyotrophic lateral sclerosis, cerebral palsy, spinocerebellar degeneration, spinal vascular diseases and other encephalomyelopathies.

Therapeutic Class
Centrally acting Skeletal Muscle Relaxants


Pharmacology

Eperisone is centrally-acting skeletal muscle relaxant used to improve myotonic symptoms.

Dosage & Administration
For adults: Usually 3 tablets per day in three divided doses after each meal. The dosage should be adjusted depending on the patient age and severity of symptoms.

Interaction
Avoid concomitant use with tolperisone HCl and methocarbamol.

Contraindications
Myonil is contraindicated in patients with a history of hypersensitivity to Eperisone Hydrochloride.

Side Effects
The side effects of Eperisone are very rare, only a few cases have been observed. These are excessive relaxation, stomachache, nausea, vertigo, anorexia, drowsiness, skin rashes, diarrhea, vomiting, indigestion, GI disturbances, insomnia, headache, constipation, etc.

Pregnancy & Lactation
Eperisone should only be used in pregnant women if the expected therapeutic benefits are evaluated to outweigh the possible risks of treatment. The safety of Eperisone has not been established in pregnant women. The drug should not be used during lactation.

Storage Conditions
Store in a cool and dry place, protect from light and moisture. Keep all medication out of reach of children.