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ডাঃ এর সিরিয়াল দিন

Locol 10mg

Tablet
Atorvastatin Calcium
Popular Pharmaceuticals Ltd

Other Strength:
- Locol 20mg

Alternative:
- Tiginor 10mg
- Anzitor 10mg
- Xelpid 10mg
- Atasin 10mg
- Lipistat 10mg
- Stacor 10mg
- Atovin 10mg
- TCL-R 10mg
- Zuvas 10mg
- Vastor 10mg
- Liptor 10mg



Locol
Indication

Prevention of cardiovascular disease
In adult patients without clinically evident coronary heart diseases, but with multiple risk factors for coronary heart diseases such as age, smoking, hypertension, low HDL-C, or a family history of early coronary heart disease,
Atorvastatin is indicated to:



Reduce the risk of myocardial infarction
Reduce the risk of stroke
Reduce the risk for revascularization procedures and angina





In patients with type 2 diabetes, without clinically evident coronary heart diseases, but with multiple risk factors for coronary heart diseases, such as, retinopathy, albuminuria, smoking, or hypertension, Atorvastatin is indicated to:



Reduce the risk of myocardial infarction
Reduce the risk of stroke



Hypercholesterolemia

Atorvastatin is indicated:
1. As an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and non-familial) and mixed dyslipidemia (Fredrickson Types IIa and IIb);
2. As an adjunct to diet for the treatment of patients with elevated serum TG levels (Fredrickson Type IV);



3. For the treatment of patients with primary dysbetalipoproteinemia (Fredrickson Type III) who do not respond adequately to diet;

4. To reduce total-C and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable;

5. As an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls, 10 to 17 years of age, with heterozygous familial hypercholesterolemia if after an adequate trial of diet therapy the following findings are present:

a. LDL-C remains 190 mg/dL or
b. LDL-C remains 160 mg/dL and:

There is a positive family history of premature cardiovascular disease or
Two or more other CVD risk factors are present in the pediatric patient


Dosage & Administration

The patient should be placed on a standard cholesterol-lowering diet before receiving Atorvastatin and should continue on the diet during treatment with Atorvastatin.
Hypercholesterolemia (Heterozygous familial and non-familial) and mixed dyslipidemia (Fredrickson Types IIa and IIb)

The recommended starting dose of Atorvastatin is 10 or 20 mg once daily. The dosage range is 10 to 80 mg once daily. Atorvastatin can be administered as a single dose at any time of the day, with or without food. Therapy should be individualized according to goal of therapy and response.



Heterozygous familial hypercholesterolemia in pediatric patients (10-17 years of age)



The recommended starting dose of Atorvastatin is 10 mg/day; the maximum recommended dose is 20 mg/day. Adjustments should be made at intervals of 4 weeks or more.


Homozygous familial hypercholesterolemia (FM)
The dosage of Atorvastatin in patients with Homozygous FH is 10 to 80 mg daily. Atorvastatin can be used as an adjunct to other lipid-lowering treatments (e.g. LDL apheresis) in these patients or if such treatments are unavailable.



Concomitant therapy

Atorvastatin may be used in combination with a bile acid binding resin for additive effect. The combination of HMG-CoA reductase inhibitors and fibrates should generally be avoided.



Dosage in patients with renal Insufficiency
Renal disease does not affect the plasma concentrations nor LDL-C reduction of Atorvastatin; thus, dosage adjustment in patients with renal dysfunction is not necessary.


Precautions

Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever. Atorvastatin should be used with caution in patients who consume substantial quantities of alcohol and/or have a history of liver disease.

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যোগাযোগ
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