Detomax 200mcg/2ml

IV Infusion
Dexmedetomidine Hydrochloride
Incepta Pharmaceuticals Ltd

Other Strength:

Alternative:



Detomax
Presentation
Detomax IV infusion: Each vial contains Dexmedetomidine Hydrochloride USP equivalent to Dexmedetomidine 200 mcg. Each normal saline bottle contains 48 ml 0.9% Sodium Chloride solution.

Description
Dexmeditomidine is a relatively selective alpha2-adrenergic agonist with sedative properties.

Indications
Dexmeditomidine is a relatively selective alpha2-adrenergic agonist indicated for:

Sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting. Administer Dexmeditomidine by continuous infusion not to exceed 24 hours.

Sedation of non-intubated patients prior to and/or during surgical and other procedures.

Dosage & Administration
Individualize and titrate Dexmeditomidine dosing to desired clinical effect.
Administer Dexmeditomidine using a controlled infusion device.
Dilute the 200 mcg/2 mL (100 mcg/mL) vial contents in 0.9% sodium chloride solution to achieve required concentration (4 mcg/mL) prior to administration.
The 200 mcg/50mL single-use bottles do not require further dilution prior to administration.

For Adult Intensive Care Unit Sedation: Generally initiate at one mcg/kg over 10 minutes, followed by a maintenance infusion of 0.2 to 0.7 mcg/kg/hour.

For Adult Procedural Sedation: Generally initiate at one mcg/kg over 10 minutes, followed by a maintenance infusion initiated at 0.6 mcg/kg/hour and titrated to achieve desired clinical effect with doses ranging from 0.2 to 1 mcg/kg/hour.
Alternative Doses: Recommended for patients over 65 years of age and awake fiberoptic intubation patients.

Precautions
Continuous monitoring is needed while patient receiving Dexmedetomidine.

Use in Pregnancy & Lactation
Pregnancy Category C

Drug Interaction
Co-administration of Dexmedetomidine with anesthetics, sedatives, hypnotics, and opioids is likely to lead to an enhancement of effects.

Over Dose
Bradycardia, hypotension and cardiac arrest is observed.

Commercial Pack
Detomax IV infusion: Each pack contains one vial (2 ml) with carton, 48 ml normal saline in a glass bottle, one infusion set, hanger and one 5 ml disposable syringe.


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